UNODC is uniquely positioned to ensure an effective and comprehensive criminal justice response to trafficking in persons and smuggling of migrants founded in the full implementation of the Protocols to the Organized Crime Convention. In addressing all aspects of these crimes within UNODC’s mandates, including research and awareness‐raising, implementation and capacity‐building and strengthening partnerships and coordination, UNODC is seeking to become the policy lead and central hub for the international community’s response. This comprehensive strategy sets out the complementary nature of UNODC’s work in preventing and combating these crimes and defines the priorities for future action and engagement.